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Medical research
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Engineered platelets can induce anti-inflammatory, immunosuppressive response, finds scientist

Engineered platelets can induce anti-inflammatory, immunosuppressive response, finds scientist

by Marlene Leung,St. Michael's HospitalCredit: Pixabay/CC0 Public DomainNew research led by a St. Michael's Hospital scientist reveals how platelets can inhibit inflammation and immune r

Engineered platelets can induce anti-inflammatory, immunosuppressive response, finds scientist

by Marlene Leung,St. Michael's HospitalCredit: Pixabay/CC0 Public DomainNew research led by a St. Michael's Hospital scientist reveals how platelets can inhibit inflammation and immune r
Making clinical guidelines work for large language models

Making clinical guidelines work for large language models

by Rachel Martin,Yale UniversityExample of a clinical decision support system integrated with large language models. Credit:npj Digital Medicine(2024). DOI: 10.1038/s41746-024-01091-

Making clinical guidelines work for large language models

by Rachel Martin,Yale UniversityExample of a clinical decision support system integrated with large language models. Credit:npj Digital Medicine(2024). DOI: 10.1038/s41746-024-01091-
One in five US cancer patients join in medical research

One in five US cancer patients join in medical research

by Dennis ThompsonMore patients these days are taking part in cancer research, a new study finds.At least one in five people with cancer (22%) participate in some form of clinical research, when all t

One in five US cancer patients join in medical research

by Dennis ThompsonMore patients these days are taking part in cancer research, a new study finds.At least one in five people with cancer (22%) participate in some form of clinical research, when all t
Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of
World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

DECEMBER 6, 2023bySt Vincent's Institute of Medical ResearchCredit: CC0 Public DomainResearchers at St Vincent's Institute of Medical Research (SVI) in Melbourne have shown that a common

World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

DECEMBER 6, 2023bySt Vincent's Institute of Medical ResearchCredit: CC0 Public DomainResearchers at St Vincent's Institute of Medical Research (SVI) in Melbourne have shown that a common
New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs
Research provides further evidence that epigenetic changes can cause type 2 diabetes

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc
AI model provides deep insights into hand movement, an essential step for development of neuroprosthetics

AI model provides deep insights into hand movement, an essential step for development of neuroprosthetics

byEcole Polytechnique Federale de LausanneThe EPFL/UNIGE AI model achieved a 100% success rate in the first phase of the competition, surpassing the closest competitor. Even in the more challeng

AI model provides deep insights into hand movement, an essential step for development of neuroprosthetics

byEcole Polytechnique Federale de LausanneThe EPFL/UNIGE AI model achieved a 100% success rate in the first phase of the competition, surpassing the closest competitor. Even in the more challeng
Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules
FDA Approves Lymphir: A New Hope for CTCL Patients

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.