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CRISPR-based mapping uncovers 'switches' for immune genes central to health

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t
States strive to get opioid overdose drug to more people

States strive to get opioid overdose drug to more people

by Anna Claire Vollers, Stateline.orgCredit: Unsplash/CC0 Public DomainPosing as shoppers, a team of researchers from the University of Mississippi called nearly 600 pharmacies across the state and as

States strive to get opioid overdose drug to more people

by Anna Claire Vollers, Stateline.orgCredit: Unsplash/CC0 Public DomainPosing as shoppers, a team of researchers from the University of Mississippi called nearly 600 pharmacies across the state and as
New drug halts growth of aggressive breast cancer in pre-clinical study

New drug halts growth of aggressive breast cancer in pre-clinical study

FEBRUARY 5, 2024by Jessica Stanley,University of AdelaideCDDD11-8 inhibits proliferation of patient-derived breast organoid models. Credit:Oncogene(2023). DOI: 10.1038/s41388-023-028

New drug halts growth of aggressive breast cancer in pre-clinical study

FEBRUARY 5, 2024by Jessica Stanley,University of AdelaideCDDD11-8 inhibits proliferation of patient-derived breast organoid models. Credit:Oncogene(2023). DOI: 10.1038/s41388-023-028
The year in opioid settlements: 5 things you need to know

The year in opioid settlements: 5 things you need to know

DECEMBER 30, 2023 Editors' notesby Aneri Pattani, KFF Health NewsCredit: Pixabay/CC0 Public DomainThis year, about $1.5 billion has landed in state and local government coffers from court settleme

The year in opioid settlements: 5 things you need to know

DECEMBER 30, 2023 Editors' notesby Aneri Pattani, KFF Health NewsCredit: Pixabay/CC0 Public DomainThis year, about $1.5 billion has landed in state and local government coffers from court settleme
Asia-Pacific gets new weapon in fight against drug-resistant TB

Asia-Pacific gets new weapon in fight against drug-resistant TB

Credit: CC0 Public DomainA faster and vastly more effective treatment for drug-resistant tuberculosis is being rolled out in the Asia-Pacific region, raising hopes of a "new era" in tackling

Asia-Pacific gets new weapon in fight against drug-resistant TB

Credit: CC0 Public DomainA faster and vastly more effective treatment for drug-resistant tuberculosis is being rolled out in the Asia-Pacific region, raising hopes of a "new era" in tackling
New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso
Colorado blames Biden team and drugmakers for delaying Canadian imports

Colorado blames Biden team and drugmakers for delaying Canadian imports

by Phil Galewitz, KFF Health NewsCredit: CC0 Public DomainColorado officials say their plan to import cheaper medicines from Canada has been stymied by opposition from drugmakers and inaction by the B

Colorado blames Biden team and drugmakers for delaying Canadian imports

by Phil Galewitz, KFF Health NewsCredit: CC0 Public DomainColorado officials say their plan to import cheaper medicines from Canada has been stymied by opposition from drugmakers and inaction by the B
Medical Forecasting

Medical Forecasting

This week, we explore AI and multimodal data's impact on healthcare. Discover advancements in disease prediction and prevention, revolutionizing early detection and personalized medicine.

Medical Forecasting

This week, we explore AI and multimodal data's impact on healthcare. Discover advancements in disease prediction and prevention, revolutionizing early detection and personalized medicine.
Research team discovers new way to generate human cartilage

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic
Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University
A new vision for AAV-delivered gene therapies

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo
Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic