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Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K
Combining genomics and metabolism identifies long-sought mitochondrial choline transporter

Combining genomics and metabolism identifies long-sought mitochondrial choline transporter

byVanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainA multidisciplinary research team has developed a discovery platform to probe the function of genes involved in metabolism

Combining genomics and metabolism identifies long-sought mitochondrial choline transporter

byVanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainA multidisciplinary research team has developed a discovery platform to probe the function of genes involved in metabolism
Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

by Vincent Jacobbi,Mayo ClinicCredit: Pixabay/CC0 Public DomainA new Mayo Clinic systematicreview, published in theJournal of Vascular Surgeryhas shed light on genetically inhe

Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

by Vincent Jacobbi,Mayo ClinicCredit: Pixabay/CC0 Public DomainA new Mayo Clinic systematicreview, published in theJournal of Vascular Surgeryhas shed light on genetically inhe
Study shows how genes in retina are regulated during development

Study shows how genes in retina are regulated during development

byNational Institutes of HealthThis image metaphorically captures the cell differentiation process during retinal organoid development. Loose yarn representing uncompacted DNA is wound by a croc

Study shows how genes in retina are regulated during development

byNational Institutes of HealthThis image metaphorically captures the cell differentiation process during retinal organoid development. Loose yarn representing uncompacted DNA is wound by a croc
Experts release the latest guide for systematic reviews of preclinical research

Experts release the latest guide for systematic reviews of preclinical research

byRadboud UniversityCredit: Unsplash/CC0 Public DomainA new publication inNature Reviews Methods Primersprovides essential guidance for conducting rigorous systematic reviews on stud

Experts release the latest guide for systematic reviews of preclinical research

byRadboud UniversityCredit: Unsplash/CC0 Public DomainA new publication inNature Reviews Methods Primersprovides essential guidance for conducting rigorous systematic reviews on stud
Lymph node research pioneers’ new approach to vaccine design for the most vulnerable

Lymph node research pioneers’ new approach to vaccine design for the most vulnerable

17 January 2024The Oxford Experimental Medicine Clinical Research Facility (EMCRF) at NDORMS has received its first volunteers as part of the LEGACY03 trial to improve vaccine design for different age

Lymph node research pioneers’ new approach to vaccine design for the most vulnerable

17 January 2024The Oxford Experimental Medicine Clinical Research Facility (EMCRF) at NDORMS has received its first volunteers as part of the LEGACY03 trial to improve vaccine design for different age
Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L
Prairie voles display signs of human-like depression, show promise as animal model

Prairie voles display signs of human-like depression, show promise as animal model

by University of Texas at El PasoSergio Iñiguez, Ph.D., a professor of psychology at The University of Texas at El Paso, points out the symptoms of depression in voles to doctoral student Minerva

Prairie voles display signs of human-like depression, show promise as animal model

by University of Texas at El PasoSergio Iñiguez, Ph.D., a professor of psychology at The University of Texas at El Paso, points out the symptoms of depression in voles to doctoral student Minerva
Predicting neurodevelopmental disease in children from parents' traits

Predicting neurodevelopmental disease in children from parents' traits

by Sam Sholtis,Pennsylvania State UniversityNeurodevelopmental and psychiatric disorders, and the genes that can lead to them, vary in a population (left, brighter red colors represent more seve

Predicting neurodevelopmental disease in children from parents' traits

by Sam Sholtis,Pennsylvania State UniversityNeurodevelopmental and psychiatric disorders, and the genes that can lead to them, vary in a population (left, brighter red colors represent more seve
New hydrogel features enhanced capabilities for treating aneurysms and halting their progression

New hydrogel features enhanced capabilities for treating aneurysms and halting their progression

by Terasaki Institute for Biomedical InnovationThe standard non-invasive treatment for patients with aneurysms is to insert a stent graft, a mesh-lined tube, into the affected blood vessel to shore up

New hydrogel features enhanced capabilities for treating aneurysms and halting their progression

by Terasaki Institute for Biomedical InnovationThe standard non-invasive treatment for patients with aneurysms is to insert a stent graft, a mesh-lined tube, into the affected blood vessel to shore up