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Medical research
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Study finds embryos in hungry mouse moms postpone development

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,
Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX
Researchers present playbook of best practices for cancer team science in the modern era

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat
Experimental compound extends life in amyotrophic lateral sclerosis mouse model

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i
A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat
Researchers uncover 'circular logic' of RNAs in Parkinson's disease

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used
What type of a relationship with an ancient person does a shared DNA fragment imply?

What type of a relationship with an ancient person does a shared DNA fragment imply?

by Shai Carmi and Harald Ringbauer,The ConversationA comparison of one chromosome’s DNA sequence between a 14th-century German Jew and two living people who uploaded their DNA to GEDmatch. Each

What type of a relationship with an ancient person does a shared DNA fragment imply?

by Shai Carmi and Harald Ringbauer,The ConversationA comparison of one chromosome’s DNA sequence between a 14th-century German Jew and two living people who uploaded their DNA to GEDmatch. Each
Common dry cleaning chemical linked to Parkinson's

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi
Study shows that the way the brain learns is different from the way that artificial intelligence systems learn

Study shows that the way the brain learns is different from the way that artificial intelligence systems learn

ARTIFICIAL INTELLIGENCEMEDICAL SCIENCESNEUROSCIENCERESEARCHSCIENCEResearchers from theMRC Brain Network Dynamics Unit and Oxford University’sDepartment of Computer Sciencehave set ou

Study shows that the way the brain learns is different from the way that artificial intelligence systems learn

ARTIFICIAL INTELLIGENCEMEDICAL SCIENCESNEUROSCIENCERESEARCHSCIENCEResearchers from theMRC Brain Network Dynamics Unit and Oxford University’sDepartment of Computer Sciencehave set ou
One in five people with cancer participate in medical research studies

One in five people with cancer participate in medical research studies

by Fred Hutchinson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers from Fred Hutchinson Cancer Center, the American Cancer Society Cancer Action Network and peer institutions released n

One in five people with cancer participate in medical research studies

by Fred Hutchinson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers from Fred Hutchinson Cancer Center, the American Cancer Society Cancer Action Network and peer institutions released n
CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death
Researchers uncover news clues about the cause of craniofacial birth defects

Researchers uncover news clues about the cause of craniofacial birth defects

byUniversity of Wisconsin-MadisonThis image of a section through the midface of a mouse embryo illustrates fusion of the tissues that form the secondary palate above the tongue. Green staining i

Researchers uncover news clues about the cause of craniofacial birth defects

byUniversity of Wisconsin-MadisonThis image of a section through the midface of a mouse embryo illustrates fusion of the tissues that form the secondary palate above the tongue. Green staining i