COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

by Matthew Woodruff,The ConversationCredit: Pixabay/CC0 Public DomainAround the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain

Updated on: April 10,2024 17

COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

by Matthew Woodruff,The ConversationCredit: Pixabay/CC0 Public DomainAround the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain

Updated on:April 10,2024 17

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Updated on: June 06,2024 6

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Updated on:June 06,2024 6

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on: May 13,2024 3

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on:May 13,2024 3

Study links early TNF inhibitor treatment to higher heart disease risk in ankylosing spondylitis patients, with caveats

by American College of RheumatologyCredit: Jean Liew et al, The Association of Early TNF Inhibitor Use with Incident Cardiovascular Events in Ankylosing Spondylitis [abstract]. Arthritis Rheumato

Updated on: June 15,2024 7

Study links early TNF inhibitor treatment to higher heart disease risk in ankylosing spondylitis patients, with caveats

by American College of RheumatologyCredit: Jean Liew et al, The Association of Early TNF Inhibitor Use with Incident Cardiovascular Events in Ankylosing Spondylitis [abstract]. Arthritis Rheumato

Updated on:June 15,2024 7

Women who are 'larks' have a lower risk of developing breast cancer

by National Cancer Research InstituteThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by To

Updated on: March 13,2024 19

Women who are 'larks' have a lower risk of developing breast cancer

by National Cancer Research InstituteThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by To

Updated on:March 13,2024 19

Researchers find genetic association for interstitial lung disease

by University of TsukubaMUC5B risk allele carrier frequency in ANCA-associated vasculitis (AAV) with and without interstitial lung disease (ILD) as well as in healthy controls in the Japanese pop

Updated on: May 19,2024 3

Researchers find genetic association for interstitial lung disease

by University of TsukubaMUC5B risk allele carrier frequency in ANCA-associated vasculitis (AAV) with and without interstitial lung disease (ILD) as well as in healthy controls in the Japanese pop

Updated on:May 19,2024 3

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on: March 07,2024 12

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on:March 07,2024 12

'Mix and match' assembly instructions guide immune cell attacks

by Walter and Eliza Hall Institute of Medical ResearchAssociate Professor Matthew Call (left) and Dr Melissa Call discovered a unique way that immune cells respond to, and kill, diseased and canc

Updated on: March 13,2024 20

'Mix and match' assembly instructions guide immune cell attacks

by Walter and Eliza Hall Institute of Medical ResearchAssociate Professor Matthew Call (left) and Dr Melissa Call discovered a unique way that immune cells respond to, and kill, diseased and canc

Updated on:March 13,2024 20

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Updated on: April 27,2024 0

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Updated on:April 27,2024 0

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024 19

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024 19

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

Updated on: January 26,2024 17

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

Updated on:January 26,2024 17

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on: April 24,2024 13

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on:April 24,2024 13