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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Mortality rate up for Koreans with rheumatoid arthritis

Mortality rate up for Koreans with rheumatoid arthritis

(HealthDay)—Korean patients with rheumatoid arthritis (RA) have increased mortality rates compared with the general population, according to a study published online Jan. 19 in theInternational

Mortality rate up for Koreans with rheumatoid arthritis

(HealthDay)—Korean patients with rheumatoid arthritis (RA) have increased mortality rates compared with the general population, according to a study published online Jan. 19 in theInternational
New method is better able to map immune response and paves way for new treatments

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari
Pain in the back: Preventing and treating spinal arthritis

Pain in the back: Preventing and treating spinal arthritis

by Dan Lea,Mayo ClinicCredit: Mayo ClinicMany types of arthritis can affect your musculoskeletal system. Joints are physical points of connection between two bones, and cartilage is the tissue t

Pain in the back: Preventing and treating spinal arthritis

by Dan Lea,Mayo ClinicCredit: Mayo ClinicMany types of arthritis can affect your musculoskeletal system. Joints are physical points of connection between two bones, and cartilage is the tissue t
Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr
RNA proofreading mistakes drive group of autoimmune diseases

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s
Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c
The PANoptosome: A new frontier in innate immune responses

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun
Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

by Flinders UniversityCredit: Unsplash/CC0 Public DomainA routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of

Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

by Flinders UniversityCredit: Unsplash/CC0 Public DomainA routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of
Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron
CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

by Impact Journals LLC(A) Immunohistochemistry (IHC) staining of testis (positive control). (B) IHC staining of colonic adenocarcinoma. (C) IHC stating of Normal colonic mucosa (negative control). Pur

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

by Impact Journals LLC(A) Immunohistochemistry (IHC) staining of testis (positive control). (B) IHC staining of colonic adenocarcinoma. (C) IHC stating of Normal colonic mucosa (negative control). Pur
'Mix and match' assembly instructions guide immune cell attacks

'Mix and match' assembly instructions guide immune cell attacks

by Walter and Eliza Hall Institute of Medical ResearchAssociate Professor Matthew Call (left) and Dr Melissa Call discovered a unique way that immune cells respond to, and kill, diseased and canc

'Mix and match' assembly instructions guide immune cell attacks

by Walter and Eliza Hall Institute of Medical ResearchAssociate Professor Matthew Call (left) and Dr Melissa Call discovered a unique way that immune cells respond to, and kill, diseased and canc
CAR T cell therapies may lead to reactivation of childhood viral infections

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca