Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on: September 04,2024 0

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on:September 04,2024 0

One step closer to tailored treatment of severe rheumatic diseases

by Aarhus UniversityThe study leads us to hope that the immunological cells and inflammatory signalling molecules in the joint of each individual patient will be able to predict the most effectiv

Updated on: June 17,2024 7

One step closer to tailored treatment of severe rheumatic diseases

by Aarhus UniversityThe study leads us to hope that the immunological cells and inflammatory signalling molecules in the joint of each individual patient will be able to predict the most effectiv

Updated on:June 17,2024 7

Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

byUniversity of TsukubaGraphical abstract. Credit:Clinical Immunology(2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in reg

Updated on: September 02,2024 0

Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

byUniversity of TsukubaGraphical abstract. Credit:Clinical Immunology(2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in reg

Updated on:September 02,2024 0

Low dose steroid use not associated with substantial weight gain or hypertension in patients with rheumatoid arthritis

by American College of PhysiciansCredit: Unsplash/CC0 Public DomainAn analysis of randomized controlled trials has found that the use of low-dose glucocorticoids was not associated with substanti

Updated on: June 17,2024 3

Low dose steroid use not associated with substantial weight gain or hypertension in patients with rheumatoid arthritis

by American College of PhysiciansCredit: Unsplash/CC0 Public DomainAn analysis of randomized controlled trials has found that the use of low-dose glucocorticoids was not associated with substanti

Updated on:June 17,2024 3

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Updated on: May 26,2024 8

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Updated on:May 26,2024 8

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on: May 05,2024 15

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on:May 05,2024 15

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on: August 08,2024 0

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on:August 08,2024 0

Ointment containing DNA molecules can combat allergic contact dermatitis

byUniversity of BonnFluorescence microscopic imaging of the skin treated with the aptamer cream: - The aptamers (here marked in pink) were applied to the top layer of the skin in the form of an

Updated on: July 06,2024 0

Ointment containing DNA molecules can combat allergic contact dermatitis

byUniversity of BonnFluorescence microscopic imaging of the skin treated with the aptamer cream: - The aptamers (here marked in pink) were applied to the top layer of the skin in the form of an

Updated on:July 06,2024 0

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024 0

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024 0

T cells: Vesicles strengthen immune response

by Ludwig Maximilian University of MunichMFG-E8-eGFP detects PS+ apoptotic and PS+ EV-decorated cells in vivo. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.22

Updated on: May 05,2024 14

T cells: Vesicles strengthen immune response

by Ludwig Maximilian University of MunichMFG-E8-eGFP detects PS+ apoptotic and PS+ EV-decorated cells in vivo. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.22

Updated on:May 05,2024 14

Gout is primary indication in about 0.2 percent of ER visits

Gout is the primary indication in about 0.2 percent of emergency department visits annually, according to a study published online Sept. 4 inArthritis Care & Research.(HealthDay)—Gout is the

Updated on: April 08,2024 14

Gout is primary indication in about 0.2 percent of ER visits

Gout is the primary indication in about 0.2 percent of emergency department visits annually, according to a study published online Sept. 4 inArthritis Care & Research.(HealthDay)—Gout is the

Updated on:April 08,2024 14

Unusual type of antibody shows ultrapotent activity against Zika

by Weill Cornell Medical CollegeZika virus particles (red) shown in African green monkey kidney cells. Credit: NIAIDAn unusual type of antibody that even at miniscule levels neutralizes the Zika

Updated on: May 07,2024 12

Unusual type of antibody shows ultrapotent activity against Zika

by Weill Cornell Medical CollegeZika virus particles (red) shown in African green monkey kidney cells. Credit: NIAIDAn unusual type of antibody that even at miniscule levels neutralizes the Zika

Updated on:May 07,2024 12