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Hematology&Oncology
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Recommendations to increase access to whole genome sequencing for children with cancer

Recommendations to increase access to whole genome sequencing for children with cancer

byWellcome Trust Sanger InstituteCredit:BMC Medical Education(2024). DOI: 10.1186/s12909-024-06219-yExperts have published a series of recommendations for improving equity of access

Recommendations to increase access to whole genome sequencing for children with cancer

byWellcome Trust Sanger InstituteCredit:BMC Medical Education(2024). DOI: 10.1186/s12909-024-06219-yExperts have published a series of recommendations for improving equity of access
Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

byUniversity of LiverpoolIntegrin αVβ6recruits HER2 and a trafficking regulatory subnetwork comprising RAB5/RAB7A/GDI2 in HER2+ breast cancer cells. Credit:Science Advances(202

Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

byUniversity of LiverpoolIntegrin αVβ6recruits HER2 and a trafficking regulatory subnetwork comprising RAB5/RAB7A/GDI2 in HER2+ breast cancer cells. Credit:Science Advances(202
Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x

Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x
Overcoming glioblastoma resistance to chemotherapy

Overcoming glioblastoma resistance to chemotherapy

byInstitute for Basic ScienceThe "onion model" illustrates how the one-by-one inactivation of the DNA repair pathways brings about changes in TMZ-induced mutational signatures. Every &

Overcoming glioblastoma resistance to chemotherapy

byInstitute for Basic ScienceThe "onion model" illustrates how the one-by-one inactivation of the DNA repair pathways brings about changes in TMZ-induced mutational signatures. Every &
Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP
Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainToday, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low

Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainToday, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low
DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

byWeill Cornell Medical CollegeCredit: CC0 Public DomainSpecially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the live

DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

byWeill Cornell Medical CollegeCredit: CC0 Public DomainSpecially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the live
Molecular 'ZIP code' draws killer T cells to brain tumors

Molecular 'ZIP code' draws killer T cells to brain tumors

by Levi Gadye,University of California, San FranciscoProgramming tissue-sensing T cells to deliver therapeutics to the brain. Credit:Science(2024). DOI: 10.1126/science.adl4237UCSF s

Molecular 'ZIP code' draws killer T cells to brain tumors

by Levi Gadye,University of California, San FranciscoProgramming tissue-sensing T cells to deliver therapeutics to the brain. Credit:Science(2024). DOI: 10.1126/science.adl4237UCSF s
Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi