Study links intestinal glycan modifications to obesity and inflammation

byChiba UniversityChst4–/–mice lacking GlcNAc-6-O-sulfation of the mucinO-glycans showed significant weight gain, increased intestinal inflammation, and significantly reduced immunoglobuli

Updated on: January 18,2024 12

Study links intestinal glycan modifications to obesity and inflammation

byChiba UniversityChst4–/–mice lacking GlcNAc-6-O-sulfation of the mucinO-glycans showed significant weight gain, increased intestinal inflammation, and significantly reduced immunoglobuli

Updated on:January 18,2024 12

New comprehensive review of biochemical markers of bone fragility in diabetes

byInternational Osteoporosis FoundationCredit: Unsplash/CC0 Public DomainThe risk of fragility fractures is increased in people with both type 1 and type 2 diabetes. While guidance for the evalu

Updated on: January 24,2024 24

New comprehensive review of biochemical markers of bone fragility in diabetes

byInternational Osteoporosis FoundationCredit: Unsplash/CC0 Public DomainThe risk of fragility fractures is increased in people with both type 1 and type 2 diabetes. While guidance for the evalu

Updated on:January 24,2024 24

Systematic study of free fatty acids reveals new roles in metabolic diseases

by Stephanie McPherson,Broad Institute of MIT and HarvardHuman pancreatic beta cells show increased membrane rigidity (indicated in red) when exposed to erucic acid, a toxic monounsaturated fatt

Updated on: January 31,2024 18

Systematic study of free fatty acids reveals new roles in metabolic diseases

by Stephanie McPherson,Broad Institute of MIT and HarvardHuman pancreatic beta cells show increased membrane rigidity (indicated in red) when exposed to erucic acid, a toxic monounsaturated fatt

Updated on:January 31,2024 18

Research finds higher disease protection in fat cells in females

byUniversity of CincinnatiCredit: CC0 Public DomainResearch from the University of Cincinnati finds a higher presence of mitochondria in fat tissue in females. The research suggests this provide

Updated on: February 19,2024 0

Research finds higher disease protection in fat cells in females

byUniversity of CincinnatiCredit: CC0 Public DomainResearch from the University of Cincinnati finds a higher presence of mitochondria in fat tissue in females. The research suggests this provide

Updated on:February 19,2024 0

Does microdosing Ozempic work? What experts are saying about the diabetes drug also used for weight loss

by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Markus Winkler from PexelsThe high price and side effects of Ozempic, the blockbuster diabetes drug also used off label for weight los

Updated on: November 07,2024 0

Does microdosing Ozempic work? What experts are saying about the diabetes drug also used for weight loss

by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Markus Winkler from PexelsThe high price and side effects of Ozempic, the blockbuster diabetes drug also used off label for weight los

Updated on:November 07,2024 0

Parkinson's, cancer, type 2 diabetes share a key element that drives disease

by Salk InstituteParkin protein (green signal) is in a different part of the cell than the mitochondria (red signal) at time 0 (left image) but then co-localizes with the mitochondria after 60 mi

Updated on: February 19,2024 16

Parkinson's, cancer, type 2 diabetes share a key element that drives disease

by Salk InstituteParkin protein (green signal) is in a different part of the cell than the mitochondria (red signal) at time 0 (left image) but then co-localizes with the mitochondria after 60 mi

Updated on:February 19,2024 16

Worldwide audit finds testosterone replacement improves blood sugar control in men with type 2 diabetes

byDiabetologiaCredit: CC0 Public DomainReal-world data from an ongoing international audit of testosterone deficiency in men with type 2 diabetes, presented at theAnnual Meeting of The Eur

Updated on: January 17,2024 16

Worldwide audit finds testosterone replacement improves blood sugar control in men with type 2 diabetes

byDiabetologiaCredit: CC0 Public DomainReal-world data from an ongoing international audit of testosterone deficiency in men with type 2 diabetes, presented at theAnnual Meeting of The Eur

Updated on:January 17,2024 16

PPARγ acetylation in macrophages impairs adipose tissue function

by Higher Education PressThe role of macrophage PPARγ acetylation in determining adipose tissue remodeling. Credit: Nicole Aaron, Tarik Zahr, Ying He, Lexiang Yu, Brent Mayfield, Utpal B Pajvani, Li Q

Updated on: February 05,2024 18

PPARγ acetylation in macrophages impairs adipose tissue function

by Higher Education PressThe role of macrophage PPARγ acetylation in determining adipose tissue remodeling. Credit: Nicole Aaron, Tarik Zahr, Ying He, Lexiang Yu, Brent Mayfield, Utpal B Pajvani, Li Q

Updated on:February 05,2024 18

Study reveals new insights into body salt handling

by Marshall University Joan C. Edwards School of MedicineProximal tubule specific Atp1a1 ablation. Scheme for generation of RPT-specific Atp1a1 knockout mouse model using a Cre/Lox approach (a). DNA g

Updated on: February 21,2024 11

Study reveals new insights into body salt handling

by Marshall University Joan C. Edwards School of MedicineProximal tubule specific Atp1a1 ablation. Scheme for generation of RPT-specific Atp1a1 knockout mouse model using a Cre/Lox approach (a). DNA g

Updated on:February 21,2024 11

Obesity treatments being restricted by cash poor local services across England, investigation finds

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainPatients in nearly half the country can't get appointments with specialist teams for weight-loss support and care, including treatme

Updated on: September 18,2024 0

Obesity treatments being restricted by cash poor local services across England, investigation finds

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainPatients in nearly half the country can't get appointments with specialist teams for weight-loss support and care, including treatme

Updated on:September 18,2024 0

First patient receives Moderna mRNA trial infusion for glycogen storage disease

by Jennifer Walker,University of ConnecticutLove Joy, a nurse at UConn Health takes Loveah Hernandez's blood pressure. Credit: Shaylee KingPrior to COVID-19 vaccines most people had never he

Updated on: February 03,2024 22

First patient receives Moderna mRNA trial infusion for glycogen storage disease

by Jennifer Walker,University of ConnecticutLove Joy, a nurse at UConn Health takes Loveah Hernandez's blood pressure. Credit: Shaylee KingPrior to COVID-19 vaccines most people had never he

Updated on:February 03,2024 22

Arterial stiffness may cause metabolic syndrome in adolescents via an increase in fasting insulin and LDL cholesterol

by University of Eastern FinlandThe presence of any three of high blood pressure, high trunk fat mass, high fasting glucose, high fasting triglyceride and low fasting high-density lipoprotein cho

Updated on: February 03,2024 22

Arterial stiffness may cause metabolic syndrome in adolescents via an increase in fasting insulin and LDL cholesterol

by University of Eastern FinlandThe presence of any three of high blood pressure, high trunk fat mass, high fasting glucose, high fasting triglyceride and low fasting high-density lipoprotein cho

Updated on:February 03,2024 22