Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on: March 28,2024 0

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on:March 28,2024 0

Shared digital NHS prescribing record could avoid nearly 1 million annual drug errors

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainImplementing a single shared digital prescribing record across the NHS in England could avoid nearly 1 million drug errors every year, s

Updated on: March 28,2024 0

Shared digital NHS prescribing record could avoid nearly 1 million annual drug errors

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainImplementing a single shared digital prescribing record across the NHS in England could avoid nearly 1 million drug errors every year, s

Updated on:March 28,2024 0

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old

Updated on: March 28,2024 0

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old

Updated on:March 28,2024 0

New species of bacteria discovered in unusual human infection

JANUARY 18, 2024byKing's College LondonHalf body FDG PET aorto – bi – iliac graft with uptake in the left periureteric region. Credit:Clinical Infection in Practice(2023). DOI: 1

Updated on: March 30,2024 6

New species of bacteria discovered in unusual human infection

JANUARY 18, 2024byKing's College LondonHalf body FDG PET aorto – bi – iliac graft with uptake in the left periureteric region. Credit:Clinical Infection in Practice(2023). DOI: 1

Updated on:March 30,2024 6

Research explores liberalization of medical marijuana and mental health in the US

by University of BaselRegulation of (medical) marijuana across US states at the end of 2018. Credit:Health Economics, Policy and Law(2024). DOI: 10.1017/S1744133124000033The approval

Updated on: April 06,2024 0

Research explores liberalization of medical marijuana and mental health in the US

by University of BaselRegulation of (medical) marijuana across US states at the end of 2018. Credit:Health Economics, Policy and Law(2024). DOI: 10.1017/S1744133124000033The approval

Updated on:April 06,2024 0

A new gene-editing system tackles complex diseases

by Michelle Franklin,University of California - San DiegoA schematic overview of multiplexed orthogonal base editing. Credit:Nature Biotechnology(2024). DOI: 10.1038/s41587-024-02240

Updated on: May 30,2024 0

A new gene-editing system tackles complex diseases

by Michelle Franklin,University of California - San DiegoA schematic overview of multiplexed orthogonal base editing. Credit:Nature Biotechnology(2024). DOI: 10.1038/s41587-024-02240

Updated on:May 30,2024 0

New platform streamlines epitope comparison in antibody research

by Tokyo Institute of TechnologyThe novel Epitope Binning-seq technology streamlines antibody epitope mapping and enables the simultaneous evaluation of large numbers of genetically encoded antib

Updated on: June 15,2024 7

New platform streamlines epitope comparison in antibody research

by Tokyo Institute of TechnologyThe novel Epitope Binning-seq technology streamlines antibody epitope mapping and enables the simultaneous evaluation of large numbers of genetically encoded antib

Updated on:June 15,2024 7

Simnotrelvir shortens time to resolution of symptoms in COVID-19

by Elana GotkineFor adults with mild-to-moderate COVID-19, early administration of simnotrelvir plus ritonavir shortens the time to sustained resolution of symptoms, according to a study published in

Updated on: March 21,2024 19

Simnotrelvir shortens time to resolution of symptoms in COVID-19

by Elana GotkineFor adults with mild-to-moderate COVID-19, early administration of simnotrelvir plus ritonavir shortens the time to sustained resolution of symptoms, according to a study published in

Updated on:March 21,2024 19

Treating tuberculosis when antibiotics no longer work

byUniversity of CologneCredit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2023.12.007Researchers have identified new antibiotic molecules that target Mycobacterium tuberculo

Updated on: January 26,2024 20

Treating tuberculosis when antibiotics no longer work

byUniversity of CologneCredit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2023.12.007Researchers have identified new antibiotic molecules that target Mycobacterium tuberculo

Updated on:January 26,2024 20

Industrial societies losing healthy gut microbes, finds study

by Ben-Gurion University of the NegevCellulose degrading gut bacteria of hominids across evolutionary time. Previously unknown human gut cellulolytic ruminococcal species are highly prevalent in

Updated on: March 28,2024 0

Industrial societies losing healthy gut microbes, finds study

by Ben-Gurion University of the NegevCellulose degrading gut bacteria of hominids across evolutionary time. Previously unknown human gut cellulolytic ruminococcal species are highly prevalent in

Updated on:March 28,2024 0

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Updated on: January 09,2024 9

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Updated on:January 09,2024 9

Follow-up finds landmark steroid study remains safe 50 years on

byUniversity of AucklandCredit: Bruno Abdiel from PexelsA study has found there are no adverse long-term cardiovascular health consequences for the now-adult children of mothers who were given c

Updated on: April 28,2024 0

Follow-up finds landmark steroid study remains safe 50 years on

byUniversity of AucklandCredit: Bruno Abdiel from PexelsA study has found there are no adverse long-term cardiovascular health consequences for the now-adult children of mothers who were given c

Updated on:April 28,2024 0